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Tracking the transcriptional host response from the acute to the regenerative phase of experimental pneumococcal meningitis

BACKGROUND: Despite the availability of effective antibiotic therapies, pneumococcal meningitis (PM) has a case fatality rate of up to 30% and causes neurological sequelae in up to half of the surviving patients. The underlying brain damage includes apoptosis of neurons in the hippocampus and necros...

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Detalles Bibliográficos
Autores principales: Wittwer, Matthias, Grandgirard, Denis, Rohrbach, Janine, Leib, Stephen L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915993/
https://www.ncbi.nlm.nih.gov/pubmed/20565785
http://dx.doi.org/10.1186/1471-2334-10-176