Cargando…

An in vitro-identified high-affinity nucleosome-positioning signal is capable of transiently positioning a nucleosome in vivo

BACKGROUND: The physiological function of eukaryotic DNA occurs in the context of nucleosomal arrays that can expose or obscure defined segments of the genome. Certain DNA sequences are capable of strongly positioning a nucleosome in vitro, suggesting the possibility that favorable intrinsic signals...

Descripción completa

Detalles Bibliográficos
Autores principales: Gracey, Lia E, Chen, Zhi-Ying, Maniar, Jay M, Valouev, Anton, Sidow, Arend, Kay, Mark A, Fire, Andrew Z
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915997/
https://www.ncbi.nlm.nih.gov/pubmed/20594331
http://dx.doi.org/10.1186/1756-8935-3-13