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An in vitro-identified high-affinity nucleosome-positioning signal is capable of transiently positioning a nucleosome in vivo
BACKGROUND: The physiological function of eukaryotic DNA occurs in the context of nucleosomal arrays that can expose or obscure defined segments of the genome. Certain DNA sequences are capable of strongly positioning a nucleosome in vitro, suggesting the possibility that favorable intrinsic signals...
Autores principales: | Gracey, Lia E, Chen, Zhi-Ying, Maniar, Jay M, Valouev, Anton, Sidow, Arend, Kay, Mark A, Fire, Andrew Z |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915997/ https://www.ncbi.nlm.nih.gov/pubmed/20594331 http://dx.doi.org/10.1186/1756-8935-3-13 |
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