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B cell depletion reduces the development of atherosclerosis in mice

B cell depletion significantly reduces the burden of several immune-mediated diseases. However, B cell activation has been until now associated with a protection against atherosclerosis, suggesting that B cell–depleting therapies would enhance cardiovascular risk. We unexpectedly show that mature B...

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Detalles Bibliográficos
Autores principales: Ait-Oufella, Hafid, Herbin, Olivier, Bouaziz, Jean-David, Binder, Christoph J., Uyttenhove, Catherine, Laurans, Ludivine, Taleb, Soraya, Van Vré, Emily, Esposito, Bruno, Vilar, José, Sirvent, Jérôme, Van Snick, Jacques, Tedgui, Alain, Tedder, Thomas F., Mallat, Ziad
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916123/
https://www.ncbi.nlm.nih.gov/pubmed/20603314
http://dx.doi.org/10.1084/jem.20100155