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Sulfatase modifying factor 1–mediated fibroblast growth factor signaling primes hematopoietic multilineage development

Self-renewal and differentiation of hematopoietic stem cells (HSCs) are balanced by the concerted activities of the fibroblast growth factor (FGF), Wnt, and Notch pathways, which are tuned by enzyme-mediated remodeling of heparan sulfate proteoglycans (HSPGs). Sulfatase modifying factor 1 (SUMF1) ac...

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Detalles Bibliográficos
Autores principales: Buono, Mario, Visigalli, Ilaria, Bergamasco, Roberta, Biffi, Alessandra, Cosma, Maria Pia
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916128/
https://www.ncbi.nlm.nih.gov/pubmed/20643830
http://dx.doi.org/10.1084/jem.20091022