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Sulfatase modifying factor 1–mediated fibroblast growth factor signaling primes hematopoietic multilineage development
Self-renewal and differentiation of hematopoietic stem cells (HSCs) are balanced by the concerted activities of the fibroblast growth factor (FGF), Wnt, and Notch pathways, which are tuned by enzyme-mediated remodeling of heparan sulfate proteoglycans (HSPGs). Sulfatase modifying factor 1 (SUMF1) ac...
Autores principales: | Buono, Mario, Visigalli, Ilaria, Bergamasco, Roberta, Biffi, Alessandra, Cosma, Maria Pia |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916128/ https://www.ncbi.nlm.nih.gov/pubmed/20643830 http://dx.doi.org/10.1084/jem.20091022 |
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