Novel mechanism for the generation of human xeno-autoantibodies against the nonhuman sialic acid N-glycolylneuraminic acid

The nonhuman sialic acid N-glycolylneuraminic acid (Neu5Gc) is metabolically incorporated into human tissues from certain mammalian-derived foods, and this occurs in the face of an anti-Neu5Gc “xeno-autoantibody” response. Given evidence that this process contributes to chronic inflammation in some...

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Detalles Bibliográficos
Autores principales: Taylor, Rachel E., Gregg, Christopher J., Padler-Karavani, Vered, Ghaderi, Darius, Yu, Hai, Huang, Shengshu, Sorensen, Ricardo U., Chen, Xi, Inostroza, Jaime, Nizet, Victor, Varki, Ajit
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916132/
https://www.ncbi.nlm.nih.gov/pubmed/20624889
http://dx.doi.org/10.1084/jem.20100575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916132/
https://www.ncbi.nlm.nih.gov/pubmed/20624889
http://dx.doi.org/10.1084/jem.20100575

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