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miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

Uncontrolled extracellular matrix production by fibroblasts in response to tissue injury contributes to fibrotic diseases, such as idiopathic pulmonary fibrosis (IPF), a progressive and ultimately fatal process that currently has no cure. Although dysregulation of miRNAs is known to be involved in a...

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Detalles Bibliográficos
Autores principales: Liu, Gang, Friggeri, Arnaud, Yang, Yanping, Milosevic, Jadranka, Ding, Qiang, Thannickal, Victor J., Kaminski, Naftali, Abraham, Edward
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916139/
https://www.ncbi.nlm.nih.gov/pubmed/20643828
http://dx.doi.org/10.1084/jem.20100035