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Hes1 regulates embryonic stem cell differentiation by suppressing Notch signaling
Embryonic stem (ES) cells display heterogeneous responses upon induction of differentiation. Recent analysis has shown that Hes1 expression oscillates with a period of about 3–5 h in mouse ES cells and that this oscillating expression contributes to the heterogeneous responses: Hes1-high ES cells ar...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916211/ https://www.ncbi.nlm.nih.gov/pubmed/20545770 http://dx.doi.org/10.1111/j.1365-2443.2010.01413.x |