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Hes1 regulates embryonic stem cell differentiation by suppressing Notch signaling

Embryonic stem (ES) cells display heterogeneous responses upon induction of differentiation. Recent analysis has shown that Hes1 expression oscillates with a period of about 3–5 h in mouse ES cells and that this oscillating expression contributes to the heterogeneous responses: Hes1-high ES cells ar...

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Detalles Bibliográficos
Autores principales: Kobayashi, Taeko, Kageyama, Ryoichiro
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916211/
https://www.ncbi.nlm.nih.gov/pubmed/20545770
http://dx.doi.org/10.1111/j.1365-2443.2010.01413.x