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Hepatitis C virus NS4 protein impairs the Th1 polarization of immature dendritic cells

Dendritic cells (DCs) in chronic hepatitis C patients display impaired function, although the details remain unclear. To investigate the hepatitis C virus (HCV) protein that has the most impact on DC function, we compared five recombinant proteins and seven HCV protein genes in modulating DC phenoty...

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Detalles Bibliográficos
Autores principales: Takaki, A, Tatsukawa, M, Iwasaki, Y, Koike, K, Noguchi, Y, Shiraha, H, Sakaguchi, K, Nakayama, E, Yamamoto, K
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916225/
https://www.ncbi.nlm.nih.gov/pubmed/19804500
http://dx.doi.org/10.1111/j.1365-2893.2009.01213.x