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Homology of SMP domains to the TULIP superfamily of lipid-binding proteins provides a structural basis for lipid exchange between ER and mitochondria

Mitochondria must uptake some phospholipids from the endoplasmic reticulum (ER) for the biogenesis of their membranes. They convert one of these lipids, phosphatidylserine, to phosphatidylethanolamine, which can be re-exported via the ER to all other cellular membranes. The mechanisms underlying the...

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Detalles Bibliográficos
Autores principales: Kopec, Klaus O., Alva, Vikram, Lupas, Andrei N.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916718/
https://www.ncbi.nlm.nih.gov/pubmed/20554689
http://dx.doi.org/10.1093/bioinformatics/btq326