FAD Mutations in Amyloid Precursor Protein Do Not Directly Perturb Intracellular Calcium Homeostasis

Disturbances in intracellular calcium homeostasis are likely prominent and causative factors leading to neuronal cell death in Alzheimer's disease (AD). Familial AD (FAD) is early-onset and exhibits autosomal dominant inheritance. FAD-linked mutations have been found in the genes encoding the p...

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Detalles Bibliográficos
Autores principales: Stieren, Emily, Werchan, Walter P., El Ayadi, Amina, Li, Fuzhen, Boehning, Darren
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916833/
https://www.ncbi.nlm.nih.gov/pubmed/20700539
http://dx.doi.org/10.1371/journal.pone.0011992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916833/
https://www.ncbi.nlm.nih.gov/pubmed/20700539
http://dx.doi.org/10.1371/journal.pone.0011992

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