Candida albicans AGE3, the Ortholog of the S. cerevisiae ARF-GAP-Encoding Gene GCS1, Is Required for Hyphal Growth and Drug Resistance

BACKGROUND: Hyphal growth and multidrug resistance of C. albicans are important features for virulence and antifungal therapy of this pathogenic fungus. METHODOLOGY/PRINCIPAL FINDINGS: Here we show by phenotypic complementation analysis that the C. albicans gene AGE3 is the functional ortholog of th...

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Detalles Bibliográficos
Autores principales: Lettner, Thomas, Zeidler, Ute, Gimona, Mario, Hauser, Michael, Breitenbach, Michael, Bito, Arnold
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916835/
https://www.ncbi.nlm.nih.gov/pubmed/20700541
http://dx.doi.org/10.1371/journal.pone.0011993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916835/
https://www.ncbi.nlm.nih.gov/pubmed/20700541
http://dx.doi.org/10.1371/journal.pone.0011993

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