NPRL2 Sensitizes Human Non-Small Cell Lung Cancer (NSCLC) Cells to Cisplatin Treatment by Regulating Key Components in the DNA Repair Pathway

NPRL2, one of the tumor suppressor genes residing in a 120-kb homozygous deletion region of human chromosome band 3p21.3, has a high degree of amino acid sequence homology with the nitrogen permease regulator 2 (NPR2) yeast gene, and mutations of NPRL2 in yeast cells are associated with resistance t...

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Detalles Bibliográficos
Autores principales: Jayachandran, Gitanjali, Ueda, Kentaro, Wang, Bingbing, Roth, Jack A., Ji, Lin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916838/
https://www.ncbi.nlm.nih.gov/pubmed/20700484
http://dx.doi.org/10.1371/journal.pone.0011994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916838/
https://www.ncbi.nlm.nih.gov/pubmed/20700484
http://dx.doi.org/10.1371/journal.pone.0011994

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