Bicyclic triterpenoid Iripallidal induces apoptosis and inhibits Akt/mTOR pathway in glioma cells

BACKGROUND: The highly resistant nature of glioblastoma multiforme (GBM) to chemotherapy prompted us to evaluate the efficacy of bicyclic triterpenoid Iripallidal against GBM in vitro. METHODS: The effect of Iripallidal on proliferation and apoptosis in glioma cell lines was evaluated by MTS, colony...

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Detalles Bibliográficos
Autores principales: Koul, Nitin, Sharma, Vivek, Dixit, Deobrat, Ghosh, Sadashib, Sen, Ellora
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916920/
https://www.ncbi.nlm.nih.gov/pubmed/20576128
http://dx.doi.org/10.1186/1471-2407-10-328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916920/
https://www.ncbi.nlm.nih.gov/pubmed/20576128
http://dx.doi.org/10.1186/1471-2407-10-328

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