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Bicyclic triterpenoid Iripallidal induces apoptosis and inhibits Akt/mTOR pathway in glioma cells

BACKGROUND: The highly resistant nature of glioblastoma multiforme (GBM) to chemotherapy prompted us to evaluate the efficacy of bicyclic triterpenoid Iripallidal against GBM in vitro. METHODS: The effect of Iripallidal on proliferation and apoptosis in glioma cell lines was evaluated by MTS, colony...

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Detalles Bibliográficos
Autores principales:	Koul, Nitin, Sharma, Vivek, Dixit, Deobrat, Ghosh, Sadashib, Sen, Ellora
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916920/ https://www.ncbi.nlm.nih.gov/pubmed/20576128 http://dx.doi.org/10.1186/1471-2407-10-328

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