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The NADPH oxidases NOX4 and DUOX2 regulate cell cycle entry via a p53-dependent pathway
Reactive oxygen species (ROS) are produced in growth factor signaling pathways leading to cell proliferation, but the mechanisms leading to ROS generation and the targets of ROS signals are not well understood. Using a focused siRNA screen to identify redox-related proteins required for growth facto...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916958/ https://www.ncbi.nlm.nih.gov/pubmed/20531308 http://dx.doi.org/10.1038/onc.2010.200 |