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The NADPH oxidases NOX4 and DUOX2 regulate cell cycle entry via a p53-dependent pathway

Reactive oxygen species (ROS) are produced in growth factor signaling pathways leading to cell proliferation, but the mechanisms leading to ROS generation and the targets of ROS signals are not well understood. Using a focused siRNA screen to identify redox-related proteins required for growth facto...

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Detalles Bibliográficos
Autores principales: Salmeen, Annette, Park, Byung Ouk, Meyer, Tobias
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916958/
https://www.ncbi.nlm.nih.gov/pubmed/20531308
http://dx.doi.org/10.1038/onc.2010.200