Cyclophosphamide- metabolizing enzyme polymorphisms and survival outcomes after adjuvant chemotherapy for node-positive breast cancer: a retrospective cohort study

INTRODUCTION: Cyclophosphamide-based adjuvant chemotherapy is a mainstay of treatment for women with node-positive breast cancer, but is not universally effective in preventing recurrence. Pharmacogenetic variability in drug metabolism is one possible mechanism of treatment failure. We hypothesize t...

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Detalles Bibliográficos
Autores principales: Gor, Priya P, Su, H Irene, Gray, Robert J, Gimotty, Phyllis A, Horn, Michelle, Aplenc, Richard, Vaughan, William P, Tallman, Martin S, Rebbeck, Timothy R, DeMichele, Angela
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917014/
https://www.ncbi.nlm.nih.gov/pubmed/20459744
http://dx.doi.org/10.1186/bcr2570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917014/
https://www.ncbi.nlm.nih.gov/pubmed/20459744
http://dx.doi.org/10.1186/bcr2570

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