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What do we learn from HER2-positive breast cancer genomic profiles?
Patients with a tumor presenting amplification of the HER2 gene are currently proposed trastuzumab (herceptin) and this has greatly changed their outcome. However, a number of HER2-positive cancers show intrinsic or acquired resistance to trastuzumab and there are clear indications that they form a...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917015/ https://www.ncbi.nlm.nih.gov/pubmed/20519027 http://dx.doi.org/10.1186/bcr2571 |