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Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics

INTRODUCTION: Breast cancer is a profoundly heterogeneous disease with respect to biologic and clinical behavior. Gene-expression profiling has been used to dissect this complexity and to stratify tumors into intrinsic gene-expression subtypes, associated with distinct biology, patient outcome, and...

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Detalles Bibliográficos
Autores principales: Jönsson, Göran, Staaf, Johan, Vallon-Christersson, Johan, Ringnér, Markus, Holm, Karolina, Hegardt, Cecilia, Gunnarsson, Haukur, Fagerholm, Rainer, Strand, Carina, Agnarsson, Bjarni A, Kilpivaara, Outi, Luts, Lena, Heikkilä, Päivi, Aittomäki, Kristiina, Blomqvist, Carl, Loman, Niklas, Malmström, Per, Olsson, Håkan, Th Johannsson, Oskar, Arason, Adalgeir, Nevanlinna, Heli, Barkardottir, Rosa B, Borg, Åke
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917037/
https://www.ncbi.nlm.nih.gov/pubmed/20576095
http://dx.doi.org/10.1186/bcr2596