The estrogen receptor influences microtubule-associated protein tau (MAPT) expression and the selective estrogen receptor inhibitor fulvestrant downregulates MAPT and increases the sensitivity to taxane in breast cancer cells

INTRODUCTION: Microtubule-associated protein tau (MAPT) inhibits the function of taxanes and high expression of MAPT decreases the sensitivity to taxanes. The relationship between estrogen receptor (ER) and MAPT in breast cancer is unclear. In this study, we examined the correlation of MAPT expressi...

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Detalles Bibliográficos
Autores principales: Ikeda, Hirokuni, Taira, Naruto, Hara, Fumikata, Fujita, Takeo, Yamamoto, Hiromasa, Soh, Junichi, Toyooka, Shinichi, Nogami, Tomohiro, Shien, Tadahiko, Doihara, Hiroyoshi, Miyoshi, Shinichiro
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917038/
https://www.ncbi.nlm.nih.gov/pubmed/20579400
http://dx.doi.org/10.1186/bcr2598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917038/
https://www.ncbi.nlm.nih.gov/pubmed/20579400
http://dx.doi.org/10.1186/bcr2598

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