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The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome
Viomycin and capreomycin belong to the tuberactinomycin family of antibiotics, which are among the most effective antibiotics against multidrug-resistant tuberculosis. Here we present two crystal structures of the 70S ribosome complexed with three tRNAs and bound to either viomycin or capreomycin at...
Autores principales: | Stanley, Robin E., Blaha, Gregor, Grodzicki, Robert L., Strickler, Michael D., Steitz, Thomas A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917106/ https://www.ncbi.nlm.nih.gov/pubmed/20154709 http://dx.doi.org/10.1038/nsmb.1755 |
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