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Asymmetrically Inherited Multidrug Resistance Transporters are Recessive Determinants in Cellular Replicative Aging

Cellular aging is known to correlate with the accumulation of many harmful agents1, but can aging also result from deterioration of certain poorly-renewed beneficial components? Here we found that a group of plasma membrane-associated transporters, belonging to the multidrug resistance (MDR) protein...

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Detalles Bibliográficos
Autores principales: Eldakak, Amr, Rancati, Giulia, Rubinstein, Boris, Paul, Parama, Conaway, Veronica, Li, Rong
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917193/
https://www.ncbi.nlm.nih.gov/pubmed/20657593
http://dx.doi.org/10.1038/ncb2085