Promoting crystallization of antibody–antigen complexes via microseed matrix screening

The application of microseed matrix screening to the crystallization of antibody–antigen complexes is described for a set of antibodies that include mouse anti-IL-13 antibody C836, its humanized version H2L6 and an affinity-matured variant of H2L6, M1295. The Fab fragments of these antibodies were c...

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Detalles Bibliográficos
Autores principales: Obmolova, Galina, Malia, Thomas J., Teplyakov, Alexey, Sweet, Raymond, Gilliland, Gary L.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2010
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917276/
https://www.ncbi.nlm.nih.gov/pubmed/20693692
http://dx.doi.org/10.1107/S0907444910026041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917276/
https://www.ncbi.nlm.nih.gov/pubmed/20693692
http://dx.doi.org/10.1107/S0907444910026041

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