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Lentiviral Vector Delivery of Human Interleukin-7 (hIL-7) to Human Immune System (HIS) Mice Expands T Lymphocyte Populations

Genetically modified mice carrying engrafted human tissues provide useful models to study human cell biology in physiologically relevant contexts. However, there remain several obstacles limiting the compatibility of human cells within their mouse hosts. Among these is inadequate cross-reactvitiy be...

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Detalles Bibliográficos
Autores principales: O'Connell, Ryan M., Balazs, Alejandro B., Rao, Dinesh S., Kivork, Christine, Yang, Lili, Baltimore, David
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917362/
https://www.ncbi.nlm.nih.gov/pubmed/20700454
http://dx.doi.org/10.1371/journal.pone.0012009