Alkylating HIV-1 Nef - a potential way of HIV intervention

BACKGROUND: Nef is a 27 KDa HIV-1 accessory protein. It downregulates CD4 from infected cell surface, a mechanism critical for efficient viral replication and pathogenicity. Agents that antagonize the Nef-mediated CD4 downregulation may offer a new class of drug to combat HIV infection and disease....

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Detalles Bibliográficos
Autores principales: Jin, Yong-Jiu, Zhang, Xiaoping, Cai, Catherine Yi, Burakoff, Steven J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917394/
https://www.ncbi.nlm.nih.gov/pubmed/20659345
http://dx.doi.org/10.1186/1742-6405-7-26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917394/
https://www.ncbi.nlm.nih.gov/pubmed/20659345
http://dx.doi.org/10.1186/1742-6405-7-26

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