Cargando…
Alkylating HIV-1 Nef - a potential way of HIV intervention
BACKGROUND: Nef is a 27 KDa HIV-1 accessory protein. It downregulates CD4 from infected cell surface, a mechanism critical for efficient viral replication and pathogenicity. Agents that antagonize the Nef-mediated CD4 downregulation may offer a new class of drug to combat HIV infection and disease....
| Autores principales: | , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917394/ https://www.ncbi.nlm.nih.gov/pubmed/20659345 http://dx.doi.org/10.1186/1742-6405-7-26 |