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Gp91(phox )(NOX2) in classically activated microglia exacerbates traumatic brain injury
BACKGROUND: We hypothesized that gp91(phox )(NOX2), a subunit of NADPH oxidase, generates superoxide anion (O(2)(-)) and has a major causative role in traumatic brain injury (TBI). To evaluate the functional role of gp91(phox )and reactive oxygen species (ROS) on TBI, we carried out controlled corti...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917406/ https://www.ncbi.nlm.nih.gov/pubmed/20659322 http://dx.doi.org/10.1186/1742-2094-7-41 |