Transformation by a nucleotide-activated P2Y receptor is mediated by activation of Gα(i), Gα(q )and Rho-dependent signaling pathways

BACKGROUND: Nucleotide-actived P2Y receptors play critical roles in the growth of tumor cells by regulating cellular proliferation, differentiation and survival. RESULTS: Here we demonstrate that an avian P2Y purinoceptor (tP2YR) with unique pharmacological and signal transduction properties induces...

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Detalles Bibliográficos
Autores principales: Singh, Anurag, Boyer, José L, Der, Channing J, Zohn, Irene E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917412/
https://www.ncbi.nlm.nih.gov/pubmed/20653955
http://dx.doi.org/10.1186/1750-2187-5-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917412/
https://www.ncbi.nlm.nih.gov/pubmed/20653955
http://dx.doi.org/10.1186/1750-2187-5-11

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