Heterologous SH3-p85β inhibits influenza A virus replication

Phosphatidylinositol 3-kinase (PI3K)/Akt signalling pathway can support the replication of influenza A virus through binding of viral NS1 protein to the Src homology 3 (SH3) domain of p85β regulatory subunit of PI3K. Here we investigated the effect of heterologously overexpressed SH3 on the replicat...

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Detalles Bibliográficos
Autores principales: Zhang, Dan-gui, Li, Wei-zhong, Wang, Ge-fei, Su, Yun, Zeng, Jun, Zhang, Chi, Zeng, Xiang-xing, Chen, Xiao-xuan, Xu, Yan-xuan, Li, Kang-sheng
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917421/
https://www.ncbi.nlm.nih.gov/pubmed/20653952
http://dx.doi.org/10.1186/1743-422X-7-170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917421/
https://www.ncbi.nlm.nih.gov/pubmed/20653952
http://dx.doi.org/10.1186/1743-422X-7-170

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