Cargando…

Heterologous SH3-p85β inhibits influenza A virus replication

Phosphatidylinositol 3-kinase (PI3K)/Akt signalling pathway can support the replication of influenza A virus through binding of viral NS1 protein to the Src homology 3 (SH3) domain of p85β regulatory subunit of PI3K. Here we investigated the effect of heterologously overexpressed SH3 on the replicat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Dan-gui, Li, Wei-zhong, Wang, Ge-fei, Su, Yun, Zeng, Jun, Zhang, Chi, Zeng, Xiang-xing, Chen, Xiao-xuan, Xu, Yan-xuan, Li, Kang-sheng
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917421/ https://www.ncbi.nlm.nih.gov/pubmed/20653952 http://dx.doi.org/10.1186/1743-422X-7-170

Ejemplares similares

Structure of Lipid Kinase p110β/p85β Elucidates an Unusual SH2-Domain-Mediated Inhibitory Mechanism
por: Zhang, Xuxiao, et al.
Publicado: (2011)

Nucleoporin 85 interacts with influenza A virus PB1 and PB2 to promote its replication by facilitating nuclear import of ribonucleoprotein
por: Ling, Yue-Huan, et al.
Publicado: (2022)

In Silico Identification of Potential Druggable Binding Sites on CIN85 SH3 Domain
por: Vittorio, Serena, et al.
Publicado: (2021)

Development of an mRNA vaccine against a panel of heterologous H1N1 seasonal influenza viruses using a consensus hemagglutinin sequence
por: Ma, Ning, et al.
Publicado: (2023)

A Drug Screening Method Based on the Autophagy Pathway and Studies of the Mechanism of Evodiamine against Influenza A Virus
por: Dai, Jian-Ping, et al.
Publicado: (2012)

C-SH2 point mutation converts p85β regulatory subunit of phosphoinositide 3-kinase to an anti-aging gene
por: Kano, Yoshio, et al.
Publicado: (2019)

Heterologous influenza vRNA segments with identical non-coding sequences stimulate viral RNA replication in trans
por: Ng, Stella SF, et al.
Publicado: (2008)

Comparative genome mining and heterologous expression of an orphan NRPS gene cluster direct the production of ashimides
por: Shi, Jing, et al.
Publicado: (2019)

Drug Screening for Autophagy Inhibitors Based on the Dissociation of Beclin1-Bcl2 Complex Using BiFC Technique and Mechanism of Eugenol on Anti-Influenza A Virus Activity
por: Dai, Jian-Ping, et al.
Publicado: (2013)

Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS
por: Havrylov, Serhiy, et al.
Publicado: (2009)

Insight into the PTEN – p85α interaction and lipid binding properties of the p85α BH domain
por: Marshall, Jeremy D.S., et al.
Publicado: (2018)

The Effect of Proline cis-trans Isomerization on the Folding of the C-Terminal SH2 Domain from p85
por: Troilo, Francesca, et al.
Publicado: (2019)

Salvianolic Acid B Inhibits Aβ Generation by Modulating BACE1 Activity in SH-SY5Y-APPsw Cells
por: Tang, Ying, et al.
Publicado: (2016)

Oxymatrine Inhibits Influenza A Virus Replication and Inflammation via TLR4, p38 MAPK and NF-κB Pathways
por: Dai, Jian-Ping, et al.
Publicado: (2018)

Inhibition of CIN85-Mediated Invasion by a Novel SH3 Domain Binding Motif in the Lysyl Oxidase Propeptide
por: Sato, Seiichi, et al.
Publicado: (2013)

Macaques vaccinated with live-attenuated SIV control replication of heterologous virus
por: Reynolds, Matthew R., et al.
Publicado: (2008)

Chimeric Virus-like Particles Co-Displaying Hemagglutinin Stem and the C-Terminal Fragment of DnaK Confer Heterologous Influenza Protection in Mice
por: Liu, Cui-Cui, et al.
Publicado: (2022)

Cancer-associated mutations in the p85α N-terminal SH2 domain activate a spectrum of receptor tyrosine kinases
por: Li, Xinran, et al.
Publicado: (2021)

Emodin Inhibition of Influenza A Virus Replication and Influenza Viral Pneumonia via the Nrf2, TLR4, p38/JNK and NF-kappaB Pathways
por: Dai, Jian-Ping, et al.
Publicado: (2017)

Stable expression of shRNA for the control of recombinant adenovirus replication
por: Lana, M.V.G., et al.
Publicado: (2023)

Inhibition of porcine transmissible gastroenteritis virus (TGEV) replication in mini-pigs by shRNA
por: Zhou, Junfang, et al.
Publicado: (2010)

Heterologous Expression of a Thermostable β-1,3-Galactosidase and Its Potential in Synthesis of Galactooligosaccharides
por: Ding, Haitao, et al.
Publicado: (2018)

Production Optimization of an Active β-Galactosidase of Bifidobacterium animalis in Heterologous Expression Systems
por: Xu, Xinxin, et al.
Publicado: (2019)

Increasing the metabolic capacity of Escherichia coli for hydrogen production through heterologous expression of the Ralstonia eutropha SH operon
por: Ghosh, Dipankar, et al.
Publicado: (2013)

Intradermal vaccination of live attenuated influenza vaccine protects mice against homologous and heterologous influenza challenges
por: Lee, Andrew Chak-Yiu, et al.
Publicado: (2021)

Codelivery of SH-aspirin and curcumin by mPEG-PLGA nanoparticles enhanced antitumor activity by inducing mitochondrial apoptosis
por: Zhou, Lin, et al.
Publicado: (2015)

shRNA-armed conditionally replicative adenoviruses: a promising approach for cancer therapy
por: Zhang, Jie, et al.
Publicado: (2016)

The origin and spread of CRF85_BC, driven by heterosexual transmission among older people in Sichuan, China
por: Su, Ling, et al.
Publicado: (2020)

EXM 85-21: 31/10 - 85
por: Malandain, E.
Publicado: (1985)

Regulation of influenza virus replication by Wnt/β-catenin signaling
por: More, Sunil, et al.
Publicado: (2018)

p85β regulates autophagic degradation of AXL to activate oncogenic signaling
por: Rao, Ling, et al.
Publicado: (2020)

Methyllycaconitine Alleviates Amyloid-β Peptides-Induced Cytotoxicity in SH-SY5Y Cells
por: Zheng, XiaoLei, et al.
Publicado: (2014)

Propofol-Induced Protection of SH-SY5Y Cells against Hydrogen Peroxide Is Associated with the HO-1 via the ERK Pathway
por: Gu, Jing, et al.
Publicado: (2013)

Developing a xylanase XYNZG from Plectosphaerella cucumerina for baking by heterologously expressed in Kluyveromyces lactis
por: Zhan, Fei Xiang, et al.
Publicado: (2014)

Plasmids Expressing shRNAs Specific to the Nucleocapsid Gene Inhibit the Replication of Porcine Deltacoronavirus In Vivo
por: Gu, Jun, et al.
Publicado: (2021)

OM-85 is an immunomodulator of interferon-β production and inflammasome activity
por: Dang, A. T., et al.
Publicado: (2017)

Saikosaponin A inhibits influenza A virus replication and lung immunopathology
por: Chen, Jianxin, et al.
Publicado: (2015)

Cloning a novel endo-1,4-β-d-glucanase gene from Trichoderma virens and heterologous expression in E. coli
por: Zeng, Rong, et al.
Publicado: (2016)

Exploring heterologous prime-boost vaccination approaches to enhance influenza control in pigs
por: Li, Chong, et al.
Publicado: (2020)

In vitro Inhibition of Border Disease Virus Replication With Lentivirus-Mediated shRNAs
por: Arani, Mohammad Javad Hajihasani, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_6ftdlvbaljj27qrv984fqe09a8