Methylation-mediated silencing and tumour suppressive function of hsa-miR-124 in cervical cancer

BACKGROUND: A substantial number of microRNAs (miRNAs) is subject to epigenetic silencing in cancer. Although epigenetic silencing of tumour suppressor genes is an important feature of cervical cancer, little is known about epigenetic silencing of miRNAs. Since DNA methylation-based silencing of hsa...

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Detalles Bibliográficos
Autores principales: Wilting, Saskia M, van Boerdonk, Robert AA, Henken, Florianne E, Meijer, Chris JLM, Diosdado, Begoňa, Meijer, Gerrit A, le Sage, Carlos, Agami, Reuven, Snijders, Peter JF, Steenbergen, Renske DM
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917428/
https://www.ncbi.nlm.nih.gov/pubmed/20579385
http://dx.doi.org/10.1186/1476-4598-9-167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917428/
https://www.ncbi.nlm.nih.gov/pubmed/20579385
http://dx.doi.org/10.1186/1476-4598-9-167

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