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Methylation-mediated silencing and tumour suppressive function of hsa-miR-124 in cervical cancer
BACKGROUND: A substantial number of microRNAs (miRNAs) is subject to epigenetic silencing in cancer. Although epigenetic silencing of tumour suppressor genes is an important feature of cervical cancer, little is known about epigenetic silencing of miRNAs. Since DNA methylation-based silencing of hsa...
Autores principales: | Wilting, Saskia M, van Boerdonk, Robert AA, Henken, Florianne E, Meijer, Chris JLM, Diosdado, Begoňa, Meijer, Gerrit A, le Sage, Carlos, Agami, Reuven, Snijders, Peter JF, Steenbergen, Renske DM |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917428/ https://www.ncbi.nlm.nih.gov/pubmed/20579385 http://dx.doi.org/10.1186/1476-4598-9-167 |
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