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Contribution of bone marrow-derived cells to the pro-inflammatory effects of protease-activated receptor-2 in colitis

OBJECTIVE: Our aim was to determine the contribution of proteinase-activated receptor-2 (PAR(2))-expressing bone marrow-derived cells on the development of colonic inflammation. MATERIALS: Chimeric mice were generated by injecting bone marrow cells from wildtype (PAR(2)(+/+)) or PAR(2) knockout mice...

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Detalles Bibliográficos
Autores principales: Hyun, Eric, Andrade-Gordon, Patricia, Steinhoff, Martin, Beck, Paul L., Vergnolle, Nathalie
Formato: Texto
Lenguaje:English
Publicado: SP Birkhäuser Verlag Basel 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917702/
https://www.ncbi.nlm.nih.gov/pubmed/20339899
http://dx.doi.org/10.1007/s00011-010-0181-9