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Impaired Synaptic Plasticity and Motor Learning in Mice with a Point Mutation Implicated in Human Speech Deficits

The most well-described example of an inherited speech and language disorder is that observed in the multigenerational KE family, caused by a heterozygous missense mutation in the FOXP2 gene [1]. Affected individuals are characterized by deficits in the learning and production of complex orofacial m...

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Detalles Bibliográficos
Autores principales: Groszer, Matthias, Keays, David A., Deacon, Robert M.J., de Bono, Joseph P., Prasad-Mulcare, Shweta, Gaub, Simone, Baum, Muriel G., French, Catherine A., Nicod, Jérôme, Coventry, Julie A., Enard, Wolfgang, Fray, Martin, Brown, Steve D.M., Nolan, Patrick M., Pääbo, Svante, Channon, Keith M., Costa, Rui M., Eilers, Jens, Ehret, Günter, Rawlins, J. Nicholas P., Fisher, Simon E.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917768/
https://www.ncbi.nlm.nih.gov/pubmed/18328704
http://dx.doi.org/10.1016/j.cub.2008.01.060