The small molecule phenamil is a modulator of adipocyte differentiation and PPARγ expression

We previously described the use of a cell-based screening approach to identify small molecules that regulate adipocyte differentiation. Here we identify the amiloride derivative phenamil as an adipogenic compound. Phenamil acutely induces expression of the key transcription factor of adipogenesis, p...

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Detalles Bibliográficos
Autores principales: Won Park, Kye, Waki, Hironori, Choi, Sung-Pil, Park, Ki-Moon, Tontonoz, Peter
Formato: Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918460/
https://www.ncbi.nlm.nih.gov/pubmed/20519739
http://dx.doi.org/10.1194/jlr.M008490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918460/
https://www.ncbi.nlm.nih.gov/pubmed/20519739
http://dx.doi.org/10.1194/jlr.M008490

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