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The small molecule phenamil is a modulator of adipocyte differentiation and PPARγ expression
We previously described the use of a cell-based screening approach to identify small molecules that regulate adipocyte differentiation. Here we identify the amiloride derivative phenamil as an adipogenic compound. Phenamil acutely induces expression of the key transcription factor of adipogenesis, p...
Autores principales: | Won Park, Kye, Waki, Hironori, Choi, Sung-Pil, Park, Ki-Moon, Tontonoz, Peter |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918460/ https://www.ncbi.nlm.nih.gov/pubmed/20519739 http://dx.doi.org/10.1194/jlr.M008490 |
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