Is BDNF sufficient for information transfer between microglia and dorsal horn neurons during the onset of central sensitization?

Peripheral nerve injury activates spinal microglia. This leads to enduring changes in the properties of dorsal horn neurons that initiate central sensitization and the onset of neuropathic pain. Although a variety of neuropeptides, cytokines, chemokines and neurotransmitters have been implicated at...

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Detalles Bibliográficos
Autores principales: Biggs, James E, Lu, Van B, Stebbing, Martin J, Balasubramanyan, Sridhar, Smith, Peter A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918544/
https://www.ncbi.nlm.nih.gov/pubmed/20653959
http://dx.doi.org/10.1186/1744-8069-6-44