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Irradiation of the potential cancer stem cell niches in the adult brain improves progression-free survival of patients with malignant glioma

BACKGROUND: Glioblastoma is the most common brain tumor in adults. The mechanisms leading to glioblastoma are not well understood but animal studies support that inactivation of tumor suppressor genes in neural stem cells (NSC) is required and sufficient to induce glial cancers. This suggests that t...

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Detalles Bibliográficos
Autores principales: Evers, Patrick, Lee, Percy P, DeMarco, John, Agazaryan, Nzhde, Sayre, James W, Selch, Michael, Pajonk, Frank
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918578/
https://www.ncbi.nlm.nih.gov/pubmed/20663133
http://dx.doi.org/10.1186/1471-2407-10-384