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Irradiation of the potential cancer stem cell niches in the adult brain improves progression-free survival of patients with malignant glioma
BACKGROUND: Glioblastoma is the most common brain tumor in adults. The mechanisms leading to glioblastoma are not well understood but animal studies support that inactivation of tumor suppressor genes in neural stem cells (NSC) is required and sufficient to induce glial cancers. This suggests that t...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918578/ https://www.ncbi.nlm.nih.gov/pubmed/20663133 http://dx.doi.org/10.1186/1471-2407-10-384 |