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Differential induction of inflammatory cytokines by dendritic cells treated with novel TLR-agonist and cytokine based cocktails: targeting dendritic cells in autoimmunity

BACKGROUND: Dendritic cells (DC) are main gate-keepers of the immune system, bridging the innate and adaptive immune system. DCs are able to mature into inflammatory DCs at sites of inflammation in both autoimmune and allergic disease, thereby sustaining a continuous activation of the adaptive immun...

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Detalles Bibliográficos
Autores principales: Jensen, Simon S, Gad, Monika
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918604/
https://www.ncbi.nlm.nih.gov/pubmed/20663192
http://dx.doi.org/10.1186/1476-9255-7-37