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The actin cytoskeleton and small G protein RhoA are not involved in flow-dependent activation of ENaC
BACKGROUND: Epithelial cells are exposed to a variety of mechanical stimuli. Epithelial Na(+ )channels (ENaC) mediate sodium transport across apical membranes of epithelial cells that line the distal nephron, airway and alveoli, and distal colon. Early investigations into stretch sensitivity of ENaC...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918634/ https://www.ncbi.nlm.nih.gov/pubmed/20663206 http://dx.doi.org/10.1186/1756-0500-3-210 |