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The actin cytoskeleton and small G protein RhoA are not involved in flow-dependent activation of ENaC

BACKGROUND: Epithelial cells are exposed to a variety of mechanical stimuli. Epithelial Na(+ )channels (ENaC) mediate sodium transport across apical membranes of epithelial cells that line the distal nephron, airway and alveoli, and distal colon. Early investigations into stretch sensitivity of ENaC...

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Detalles Bibliográficos
Autores principales: Karpushev, Alexey V, Ilatovskaya, Daria V, Staruschenko, Alexander
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2918634/
https://www.ncbi.nlm.nih.gov/pubmed/20663206
http://dx.doi.org/10.1186/1756-0500-3-210