The Matricellular Protein CCN1/CYR61 Induces Fibroblast Senescence and Restricts Fibrosis in Cutaneous Wound Healing

Cellular senescence is a recognised mechanism of tumor suppression; however, its contribution to other pathologies is not well understood. We show that the matricellular protein CCN1/CYR61, which is dynamically expressed at sites of wound repair, can induce fibroblast senescence through its cell adh...

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Detalles Bibliográficos
Autores principales: Jun, Joon-Il, Lau, Lester F.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919364/
https://www.ncbi.nlm.nih.gov/pubmed/20526329
http://dx.doi.org/10.1038/ncb2070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919364/
https://www.ncbi.nlm.nih.gov/pubmed/20526329
http://dx.doi.org/10.1038/ncb2070

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