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Comparison of Microscopy and Alamar Blue Reduction in a Larval Based Assay for Schistosome Drug Screening

BACKGROUND: In view of the current widespread use of and reliance on a single schistosomicide, praziquantel, there is a pressing need to discover and develop alternative drugs for schistosomiasis. One approach to this is to develop High Throughput in vitro whole organism screens (HTS) to identify hi...

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Detalles Bibliográficos
Autores principales: Mansour, Nuha R., Bickle, Quentin D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919390/
https://www.ncbi.nlm.nih.gov/pubmed/20706580
http://dx.doi.org/10.1371/journal.pntd.0000795