Chitosan Modification of Adenovirus to Modify Transfection Efficiency in Bovine Corneal Epithelial Cells

BACKGROUND: The purpose of this study is to modulate the transfection efficiency of adenovirus (Ad) on the cornea by the covalent attachment of chitosan on adenoviral capsids via a thioether linkage between chitosan modified with 2-iminothiolane and Ad cross-linked with N-[γ-maleimidobutyryloxy]succ...

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Detalles Bibliográficos
Autores principales: Wang, I-Jong, Jhuang, Min-Chao, Chen, Yu-Hsin, Yeh, Lung-Kun, Liu, Chia-Yang, Young, Tai-Horng
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919409/
https://www.ncbi.nlm.nih.gov/pubmed/20711466
http://dx.doi.org/10.1371/journal.pone.0012085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919409/
https://www.ncbi.nlm.nih.gov/pubmed/20711466
http://dx.doi.org/10.1371/journal.pone.0012085

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