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Chitosan Modification of Adenovirus to Modify Transfection Efficiency in Bovine Corneal Epithelial Cells

BACKGROUND: The purpose of this study is to modulate the transfection efficiency of adenovirus (Ad) on the cornea by the covalent attachment of chitosan on adenoviral capsids via a thioether linkage between chitosan modified with 2-iminothiolane and Ad cross-linked with N-[γ-maleimidobutyryloxy]succ...

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Detalles Bibliográficos
Autores principales:	Wang, I-Jong, Jhuang, Min-Chao, Chen, Yu-Hsin, Yeh, Lung-Kun, Liu, Chia-Yang, Young, Tai-Horng
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919409/ https://www.ncbi.nlm.nih.gov/pubmed/20711466 http://dx.doi.org/10.1371/journal.pone.0012085

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