Optic Nerve Compression and Retinal Degeneration in Tcirg1 Mutant Mice Lacking the Vacuolar-Type H(+)-ATPase a3 Subunit

BACKGROUND: Vacuolar-type proton transporting ATPase (V-ATPase) is involved in the proper development of visual function. Mutations in the Tcirg1 (also known as Atp6V0a3) locus, which encodes the a3 subunit of V-ATPase, cause severe autosomal recessive osteopetrosis (ARO) in humans. ARO is often ass...

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Detalles Bibliográficos
Autores principales: Kawamura, Nobuyuki, Tabata, Hiroyuki, Sun-Wada, Ge-Hong, Wada, Yoh
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919411/
https://www.ncbi.nlm.nih.gov/pubmed/20711468
http://dx.doi.org/10.1371/journal.pone.0012086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919411/
https://www.ncbi.nlm.nih.gov/pubmed/20711468
http://dx.doi.org/10.1371/journal.pone.0012086

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