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Integrating Ion Mobility Mass Spectrometry with Molecular Modelling to Determine the Architecture of Multiprotein Complexes

Current challenges in the field of structural genomics point to the need for new tools and technologies for obtaining structures of macromolecular protein complexes. Here, we present an integrative computational method that uses molecular modelling, ion mobility-mass spectrometry (IM-MS) and incompl...

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Detalles Bibliográficos
Autores principales: Politis, Argyris, Park, Ah Young, Hyung, Suk-Joon, Barsky, Daniel, Ruotolo, Brandon T., Robinson, Carol V.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919415/
https://www.ncbi.nlm.nih.gov/pubmed/20711472
http://dx.doi.org/10.1371/journal.pone.0012080