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Lack of Guanylate Cyclase C results in increased mortality in mice following liver injury

BACKGROUND: Guanylate Cyclase C (GC-C) expression in the intestine plays a role in the regulation of fluid and ion transport, as well as epithelial cell apoptosis and proliferation. In the adult rat liver, GC-C expression is increased in response to injury. We hypothesized that GC-C is required for...

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Detalles Bibliográficos
Autores principales: Mann, Elizabeth A, Shanmukhappa, Kumar, Cohen, Mitchell B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919440/
https://www.ncbi.nlm.nih.gov/pubmed/20678221
http://dx.doi.org/10.1186/1471-230X-10-86