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Transactivation of PDGFRβ by dopamine D4 receptor does not require PDGFRβ dimerization

Growth factor-induced receptor dimerization and cross-phosphorylation are hallmarks of signal transduction via receptor tyrosine kinases (RTKs). G protein-coupled receptors (GPCRs) can activate RTKs through a process known as transactivation. The prototypical model of RTK transactivation involves li...

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Detalles Bibliográficos
Autores principales: Chi, Sum Shing, Vetiska, Sandra M, Gill, Robin S, Hsiung, Marilyn S, Liu, Fang, Van Tol, Hubert HM
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919524/
https://www.ncbi.nlm.nih.gov/pubmed/20659339
http://dx.doi.org/10.1186/1756-6606-3-22