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The extracellular matrix microtopography drives critical changes in cellular motility and Rho A activity in colon cancer cells

We have shown that the microtopography (mT) underlying colon cancer changes as a tumor de-differentiates. We distinguish the well-differentiated mT based on the increasing number of "pits" and poorly differentiated mT on the basis of increasing number of "posts." We investigated...

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Detalles Bibliográficos
Autores principales: Rapier, Rebecca, Huq, Jameela, Vishnubhotla, Ramana, Bulic, Marinka, Perrault, Cecile M, Metlushko, Vitali, Cho, Michael, Tay, Roger Tran Son, Glover, Sarah C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919527/
https://www.ncbi.nlm.nih.gov/pubmed/20667086
http://dx.doi.org/10.1186/1475-2867-10-24